Research Article
ABCC4 Variants Modify Susceptibility to Kawasaki Disease in a Southern Chinese Population
Table 3
Stratification analysis of susceptibility in Kawasaki disease patients.
| Variables | Combined effect of risk genotypes (patients/controls) | valuea | OR (95% CI) | value | Adjusted OR (95% CI) | valueb | 0–4 | 5-6 |
| Age, months | <12 | 163/162 | 22/15 | 0.2818 | 1.46 (0.73–2.91) | 0.2854 | 1.46 (0.73–2.91) | 0.2855 | 12–60 | 475/516 | 52/34 | 0.0253 | 1.66 (1.06–2.61) | 0.0270 | 1.65 (1.05–2.59) | 0.0296 | >60 | 53/44 | 10/3 | 0.1155 | 2.77 (0.72–10.68) | 0.1397 | 3.52 (0.87–14.33) | 0.0790 | Gender | Male | 477/488 | 47/37 | 0.2510 | 1.30 (0.83–2.04) | 0.2526 | 1.31 (0.84–2.06) | 0.2378 | Female | 214/234 | 37/15 | 0.0012 | 2.70 (1.44–5.05) | 0.0020 | 2.69 (1.43–5.03) | 0.0021 | Coronary artery outcomes | CAA | 91/722 | 12/52 | 0.0904 | 1.83 (0.94–3.56) | 0.0744 | 1.84 (0.94–3.60) | 0.0748 | CAL | 170/722 | 17/52 | 0.2727 | 1.39 (0.78–2.46) | 0.2609 | 1.39 (0.78–2.47) | 0.2619 | NCAL | 430/722 | 55/52 | 0.0047 | 1.78 (1.19–2.64) | 0.0046 | 1.77 (1.18–2.63) | 0.0053 |
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aχ2 test for genotype distributions between Kawasaki disease patients and controls; badjusted for age and gender.
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