Research Article

Methylglyoxal: A Relevant Marker of Disease Activity in Patients with Rheumatoid Arthritis

Table 2

Biological parameters of patients with rheumatoid arthritis (RA) and control subjects.

RA patients ()Control subjects ()

BMI (kg/m2)29.9 ± 7.624.8 ± 4.3<0.001
hs-CRP (mg/L)9 (5–15)0 (0–5)<0.001
Glucose (mmol/L)4.5 ± 1.74.3 ± 0.2NS
Triglyceride (mmol/L)1.6 (1.1–2.1)1.1 (0.8–1.4)<0.001
Total cholesterol (mmol/L)4.3 (3.7–4.8)4.4 (4.1–5.3)NS
HDL cholesterol (mmol/L)1.3 (1.1–1.5)0.9 (0.8–1.2)0.001
LDL cholesterol (mmol/L)2.5 (2.1–3)2.7 (2.4–3)NS
Creatinine (μmol/L)64.6 ± 23.664.5 ± 19.3NS
MGO (ng/mL)137.6 ± 76.680.4 ± 25.2<0.001
sRAGE (ng/mL)4.1 ± 1.45.4 ± 1.70.020

Data represent means ± SD or median (quartile range). NS: not significant.