Evaluation of Serum Des-Gamma-Carboxy Prothrombin for the Diagnosis of Hepatitis B Virus-Related Hepatocellular Carcinoma: A Meta-Analysis

Table 3

Summary of methodological quality of the included studies on the basis of the review authors’ judgments on the items in the QUADAS checklist for each study.

QUADAS	Number
	1	2	3	4	5	6
Representative patient spectrum?	No	No	No	No	No	No
Selection criteria	Unclear	Yes	Unclear	Unclear	Yes	Yes
Acceptable reference standard?	Yes	Yes	Yes	Yes	Yes	Yes
Acceptable delay between tests?	Yes	Yes	Yes	Yes	Yes	Yes
Partial verification avoided?	Yes	Yes	Yes	Yes	Yes	Yes
Differential verification avoided?	Yes	Yes	Yes	Yes	Yes	Yes
Incorporation avoided?	Yes	Yes	Yes	Yes	Yes	Yes
Index test execution	Yes	Yes	Yes	Yes	Yes	Yes
Reference standard execution	Yes	Yes	Yes	Yes	Yes	Yes
Reference standard results blinded?	Yes	Yes	Yes	Yes	Yes	Yes
Index test results blinded?	Yes	Yes	Yes	Yes	Yes	Yes
Relevant clinical information?	Yes	Yes	Yes	Yes	Yes	Yes
Quality of the studies	A	A	A	A	A	A