Research Article
Significance of Serum p53 Antibody as a Tumor Marker in Colorectal Cancer
| | Preoperative S-p53Ab | value | <1.3 () | ≥1.3 () | | % | | % |
| Age (years) | | | 0.592 | Gender | | | | | 0.349 | Male | 74 | 60.2 | 19 | 51.4 | | Female | 49 | 39.8 | 18 | 48.6 | | Location of tumor | | | | | 0.022 | Colon | 80 | 65.0 | 16 | 43.2 | | Rectum | 43 | 35.0 | 21 | 56.8 | | Depth of tumor | | | | | 0.185 | T1/T2 | 52 | 42.3 | 11 | 29.7 | | T3/T4 | 71 | 57.7 | 26 | 70.3 | | Status of lymph node | | | | | 0.184 | Positive | 76 | 61.8 | 18 | 48.6 | | Negative | 47 | 38.2 | 19 | 51.4 | | Status of lymphatic invasion | | | | | 0.839 | Positive | 87 | 70.7 | 27 | 73.0 | | Negative | 36 | 29.3 | 10 | 27.0 | | Status of vessel invasion | | | | | 0.443 | Positive | 77 | 62.6 | 20 | 54.1 | | Negative | 46 | 37.4 | 17 | 45.9 | | Stage | | | | | 0.324 | 1 | 35 | 28.5 | 10 | 27.0 | | 2 | 41 | 33.3 | 7 | 18.9 | | 3 | 40 | 32.5 | 19 | 51.4 | | 4 | 7 | 5.7 | 1 | 2.7 | | CEA | | | | | 0.176 | Positive | 43 | 35.0 | 18 | 48.6 | | Negative | 80 | 65.0 | 19 | 51.4 | | CA19-9 | | | | | 1.000 | Positive | 9 | 7.3 | 2 | 5.4 | | Negative | 114 | 92.7 | 35 | 94.6 | | Recurrence (excluding stage 4) | | | | | 0.275 | Positive | 15 | 12.9 | 6 | 16.7 | | Negative | 101 | 87.1 | 30 | 83.3 | |
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