Research Article

Altered Levels of mRNAs for Calcium-Binding/Associated Proteins, Annexin A1, S100A4, and TMEM64, in Peripheral Blood Mononuclear Cells Are Associated with Osteoporosis

Table 4

Summary of statistical analysis on participants without nonosteoporotic medical disorders.

mRNACompared sample groups ( = number of participants)95% confidence interval value (Bonferroni correction)

Annexin A1Nonosteoporotic control () vs. osteopenia ()0.176 to 0.477<0.0001
Nonosteoporotic control () vs. osteoporosis ()0.202 to 0.557<0.0001
Osteoporosis () vs osteopenia ()-0.206 to 0.10.491


TMEM64Nonosteoporotic control () vs. osteopenia ()-0.013 to 0.0750.166
Nonosteoporotic control () vs. osteoporosis ()0.013 to 0.1170.016
Osteoporosis () vs osteopenia ()-0.078 to 0.010.132

S100A4Nonosteoporotic control () vs. osteopenia ()-0.224 to 0.540.413
Nonosteoporotic control () vs. osteoporosis ()-0.077 to 0.8280.102
Osteoporosis () vs. osteopenia ()-0.608 to 0.1720.269