Research Article
Loss of SDC1 Expression Is Associated with Poor Prognosis of Colorectal Cancer Patients in Northern China
Table 2
Relationship between SDC1 immunoreactivity and clinicopathological characteristics, 477 CRC cases.
| | Clinical information | Total | SDC1L
Case (%) | SDC1M
Case (%) | SDC1H
Case (%) | | |
| | Age, yr | | <60.5 | 211 | 67 (32) | 93 (44) | 51 (24) | 2.13 | 0.345 | | >60.5 | 266 | 73 (27) | 135 (51) | 58 (22) | | Gender | | Female | 227 | 69 (30) | 110 (49) | 48 (21) | 0.752 | 0.686 | | Male | 250 | 71 (28) | 118 (47) | 61 (24) | | Tumor size, cm | | ≤4 | 306 | 92 (30) | 138 (45) | 76 (25) | 2.924 | 0.232 | | >4 | 171 | 48 (28) | 90 (53) | 33 (19) | | Histological grade (differentiation) (miss samples, ) | | Well | 226 | 75 (33) | 111 (49) | 40 (18) | 8.12 | 0.017 | | Moderately or poorly | 235 | 59 (25) | 110 (47) | 66 (28) | | TNM stage (T) | | 1-2 | 69 | 14 (20) | 22 (32) | 33 (48) | 28.55 | ≤0.001 | | 3-4 | 408 | 126 (31) | 206 (50) | 76 (19) | | Lymph node metastasis | | N0 | 290 | 66 (23) | 140 (48) | 84 (29) | 23.088 | ≤0.001 | | N1-3 | 187 | 74 (40) | 88 (47) | 25 (13) | | Location (miss samples, ) | | Left | 49 | 17 (35) | 23 (47) | 9 (18) | 1.123 | 0.570 | | Right | 142 | 38 (27) | 74 (52) | 30 (21) |
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L: low expression; M: moderate expression; H: high expression; statistical method: chi-square test.
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