Research Article
Tumor Mutation Load: A Novel Independent Prognostic Factor in Stage IIIA-N2 Non-Small-Cell Lung Cancer
Table 1
Cox proportional hazards analysis for progression-free survival in stage IIIA-N2 NSCLC patients.
| | | Sx | Wald | OR (95% CI) | |
| Gender (male, female) | 0.31966 | 0.388585 | 0.822626 | 1.4 (0.64-2.9) | 0.417 | Age, yr (≤60, >60) | -0.37059 | 0.496416 | -0.74654 | 0.69 (0.26-1.8) | 0.438 | Smoking (Y, N) | -0.83781 | 0.394112 | -2.12581 | 0.43 (0.2-0.94) | 0.031 | KPS (>80, ≤80) | -0.24517 | 0.388775 | -0.63062 | 0.78 (0.37-1.7) | 0.527 | Largest tumor diameter (<3, 3-4.9, and ≥5) | -0.02777 | 0.28055 | -0.099 | 0.97 (0.56-1.7) | 0.921 | Histology (adenocarcinoma, nonadenocarcinoma) | 0.15502 | 0.470391 | 0.329556 | 1.2 (0.46-2.9) | 0.738 | pT status (T1-2, T3) | -0.23663 | 0.543001 | -0.43579 | 0.79 (0.27-2.3) | 0.654 | cN2 (Y, N) | 0.356603 | 0.380638 | 0.937093 | 1.4 (0.68-3) | 0.350 | Tumor differentiation (well differentiated, poorly differentiated) | -0.57978 | 0.484415 | -1.19686 | 0.56 (0.22-1.4) | 0.253 | Met mutation (Y, N) | 0.431686 | 0.507633 | 0.850389 | 1.5 (0.57-4.2) | 0.415 | Mutation | -0.88498 | 0.397069 | -2.22878 | 0.41 (0.19-0.9) | 0.028 | Mutation | -0.78888 | 0.407384 | -1.93645 | 0.45 (0.2-1) | 0.045 |
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