Plasma Fibrin Clot Properties Are Unfavorably Altered in Women following Venous Thromboembolism Associated with Combined Hormonal Contraception

Table 2

Comparison of fibrin clot properties in the contraception-related VTE group regarding type of contraception.

Variable	Type of contraception
	CHC 2^nd ()	CHC 3^rd ()	Transdermal ()
s (10^–9cm^2)				0.36
Lag phase (s)				0.90
ΔAbsmax (405 nm)				0.26
CLT (min)				0.63
D-Drate (mg/L/min)				0.007
D-Dmax (mg/L^A)	4.0 (3.4-4.1)	3.70 (3.4-4.2)	3.66 (3.3-3.7)	0.05

Data are shown as or median (interquartile range). Abbreviations: CHC, combined hormonal contraception containing estrogen plus 2^nd- or 3^rd-generation progesterone; ΔAbs_max, maximum absorbance at the plateau phase; CLT, clot lysis time; D-D_max, maximum D-dimer levels in the lysis assay; D-D_rate, maximum rate of increase in D-dimer levels in the lysis assay; _s, fibrin clot permeability coefficient.