A Genomic-Clinicopathologic Nomogram Predicts Survival for Patients with Laryngeal Squamous Cell Carcinoma

Table 3

Assessing the prognostic performance of the TNM stage, lncRNA signature, and nomogram.

Model	Homogeneity, monotonicity, and discriminatory ability
	Likelihood ratio (LR) test	Linear trend test	C-index (95% CI)	Akaike information criterion (AIC)
TNM stage	00.5	00.5	0.53 (0.45-0.61)	380.3
lncRNA signature	21.4	46.9	0.78 (0.71-0.85)	355.0
Nomogram	48.0	71.7	0.82 (0.77-0.87)	332.4

Higher homogeneity likelihood ratio indicates a smaller difference within the staging system, and it means better homogeneity. Higher discriminatory ability linear trend indicates a higher linear trend between staging systems, and it means a better discriminatory ability and gradient monotonicity. A higher C-index means better discriminatory ability. Smaller AIC values indicate better optimistic prognostic stratification.