Overexpression of UDP-Glucose 4-Epimerase Is Associated with Differentiation Grade of Gastric Cancer

Table 1

Association between UDP glucose 4-epimerase staining with the main clinical-pathological characteristics classified by immunohistochemistry in 71 samples of primary tumor of gastric cancer.

Clinical and pathological parameters	UDP-glucose 4-epimerase (+)	UDP-glucose 4-epimerase (-)	value
	(%)	(%)
Age (years)^a			0.453
<60	22 (30.9)	13 (18.3)
≥60	26 (36.6)	10 (14.1)
Gender^b			0.287
Female	14 (19.7)	10 (14.1)
Male	34 (47.9)	13 (18.3)
Initial treatment^c			0.166
I	43 (60.6)	23 (32.3)
III	5 (7.0)	0 (0)
Surgical staging^d (TNM)			0.151
(I and II)	10 (14.1)	9 (12.7)
(III and IV)	38 (53.5)	14 (19.7)
Lymph node involvement^e			0.299
Yes	32 (45.0)	12 (16.9)
No	16 (22.5)	11 (15.5)
Nodal status^f			0.599
>0.3	19 (26.8)	7 (9.8)
<0.3	29 (40.8)	16 (22.5)
Histological grade^g			<0.0001
GI+GII	32 (45.0)	3 (4.2)
GIII	16 (22.5)	20 (28.2)
Lauren classification^h			0.0328
Intestinal	26 (38.2)	7 (10.2)
Diffuse	19 (28)	16 (23.5)
Chemotherapy^i			0.452
Yes	28 (39.4)	11 (15.5)
No	20 (28.2)	12 (16.9)
Radiotherapy^j			1.000
Yes	15 (21.1)	7 (9.8)
No	33 (46.5)	16 (22.5)
Relapse^l			0.220
Yes	8 (11.3)	7 (9.8)
No	40 (56.3)	16 (22.5)
H. pylori infection^m			0,707
Yes	7 (10.4)	2 (3.0)
No	37 (55.2)	21 (31.3)

Fisher’s exact test. ^hLauren Classification analyzed in 68 cases. ^mH. pylori infection was analyzed in 67 cases.