TFAP4 Promotes Hepatocellular Carcinoma Invasion and Metastasis via Activating the PI3K/AKT Signaling Pathway

Table 1

Correlation between clinicopathological parameters and TFAP4 expression in HCC patients.

Clinicopathological parameters	Cases ()	TFAP4 expression		value
		High	Low
Age (year)
<60	176	85	91	0.536
≥60	41	22	19
Gender
Male	194	100	94	0.056
Female	23	7	16
HBsAg
Positive	183	92	91	0.510
Negative	34	15	19
AFP (μg/l)
<400	135	65	70	0.661
≥400	82	42	40
Tumor size (maximal diameter)
<5cm	107	52	55	0.836
≥5cm	110	55	55
Number of tumors
Solitary	181	87	94	0.412
Multiple	36	20	16
Encapsulation
Destructed	74	40	34	0.315
Intact	143	67	76
Vascular invasion
Yes	191	17	9	0.081
No	26	90	101
TNM stage
I-II	184	92	92	0.631
III	33	15	18
BCLC stage
0-A	177	84	93	0.251
B	40	23	17
Differentiated
I-II	173	88	85	0.363
III-IV	44	19	25
Micrometastasis
Yes	16	10	6	0.273
No	201	97	104