Genetic Polymorphisms of IFNG and IFNGR1 with Latent Tuberculosis Infection

Table 2

Basic information of studied SNPs.

Gene/SNPs	Chromosome	Location	Functional consequence	MA	MAF	MA	MAF	HWE
				LTBI		HCS		LTBI	HC
IFNG
rs1861494T>C	12	68551409	Intron 3	C	0.30	C	0.36	0.797	0.614
rs2069718A>G	12	68550162	Intron 3	G	0.17	G	0.13	0.320	0.914
IFNGR1
rs1327475G>A	6	137536455	5 flanking	C	0.10	C	0.13	0.291	0.103
rs2234711G>A	6	137540520	5 UTR_exon1	G	0.41	G	0.34	0.961	0.651
rs3799488T>C	6	137519780	Intron 6	C	0.27	C	0.29	0.804	0.976
rs9376267C>T	6	137531031	Intron 1	C	0.46	C	0.43	0.801	0.860

Abbreviations: SNP: single-nucleotide polymorphism; LTBI: latent tuberculosis infection; HCS: healthy control subjects; MA: minor allele; MAF: minor allele frequency; HWE: Hardy–Weinberg equilibrium.