Research Article
Assessment of Liver Fibrosis with the Use of Elastography in Paediatric Patients with Diagnosed Cystic Fibrosis
Table 2
The clinical picture of the examined patients with diagnosed cystic fibrosis.
| | Values of total examined group
| Patients with CFLD
(subgroup 1)
(39%) | Patients without CFLD
(subgroup 2)
(61%) | Normal elastography
F0-F1
(53.7%) | Abnormal elastography
F2-F4
(46.3%) |
| | Age (years) | 2.0-21.0 (mean: 9.6) | 2.00-18 (mean: 9.31) | 2.5-21.0 (mean: 9.88) | 2.5-21.0 (mean: 9.42) | 2.0-18.0 (mean: 9.74) | | NS | NS | | Sex: female/male () | 24 (58.5%)/17 (41.5%) | 9 (56.25%)/7 (43.75%) | 15 (60%)/10 (40%) | 14 (63.3%)/8 (36.7%) | 10 (45.5%)/9 (54.5%) | | NS | NS | | Mutation ( (%)) | | | | | | | delF508/delF508 | 23/41 (56.1%) | 11/16 (68.75%) | 12/25 (48%) | 10/22 (45.5%) | 13/19 (68.4%) | | delF508/other | 15/41 (36.6%) | 4/16 (25%) | 11/25 (44%) | 10/22 (45.5%) | 5/19 (26.3%) | | Other | 3/41 (7.3%) | 1/16 (6.25%) | 2/25 (8%) | 2/22 (9%) | 1/19 (5.3%) | | NS | NS | | Shwachman-Kulczycki score (pts) | 74.81 (range 50-110) | 72.36 (range 50-105) | 78.21 (range 55-110) | 77.33 (55-110) | 75.42 (50-105) | | NS | NS | | Clinical features ( (%)) | | | | | | | Pancreatic insufficiency | 36/41 (87.8%) | 13/16 (81.25%) | 23/25 (92%) | 20/22 (90.0%) | 16/19 (84.2%) | | NS | NS | | Symptoms from the respiratory tract/recurrent respiratory tract infection | 38/41 (92.7%) | 14/16 (87.5%) | 24/25 (96%) | 20/22 (90%) | 18/19 (94.7%) | | NS | NS | | Malnutrition (, taking into account age, sex, and population) | 14/41 (34.1%) | 7/16 (43.75%) | 7/25 (28%) | 5/22 (22.7%) | 9/19 (47.4%) | | NS | | | Liver dysfunction | 16/41 (39.0%) | 16/41 (39.0%) | 0/25 (0%) | 0/22 (0%) | 16/19 (84.2%) | | Salt loss syndrome | 7/41 (17.1%) | 3/16 (18.75%) | 4/25 (16%) | 4/22 (18.2%) | 3/19 (15.8%) | | NS | NS | | History of meconium ileus/treated surgically | 6/41 (14.6%) | 2/16 (12.5%) | 4/25 (16%) | 4/22 (18.2%) | 2/19 (10.5%) | | NS | NS |
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