Alterations of Hormone-Sensitive Adenylyl Cyclase System in the Tissues of Rats with Long-Term Streptozotocin Diabetes and the Influence of Intranasal Insulin

Table 1

Body weight, plasma glucose, and plasma insulin levels in control rats without (Group C) and with (Group CI) I-I treatment and in rats with long-term, 7-month, STZ T1DM without (Group D) and with (Group DI) I-I treatment.

Groups of Rats	Body Weight (g)	Plasma Glucose (mM)	Plasma Insulin (ng mL^−1)
Group C (n = 8)	412 ± 27; (C-D, P = 0.0018; C-CI, P = 0.3835)	4.9 ± 0.5; (C-D, P = 0.0003; C-CI, P = 0.9913)	2.2 ± 0.3; (C-D, P = 10^−9; C-CI, P = 0.0017)
Group CI (n = 7)	428 ± 39; (CI-DI, P = 0.0234)	4.9 ± 0.7; (CI-DI, P = 0.0164)	1.5 ± 0.4; (CI-DI, P = 0.00008)
Group D (n = 8)	354 ± 32; (D-DI, P = 0.1497)	16.7 ± 5.0; (D-DI, P = 0.0458)	0.3 ± 0.2; (D-DI, P = 0.8523)
Group DI (n = 7)	379 ± 30	11.0 ± 4.9	0.4 ± 0.2

Values are expressed as the mean ± standard deviation.