Therapeutic Improvement of Scarring: Mechanisms of Scarless and Scar-Forming Healing and Approaches to the Discovery of New Treatments
Figure 4
Gene expression in models of incisional wounds and scars in rat and man demonstrate molecular comparability heatmaps of samples of normal skin, wounds, and scars following 1 cm incisional wounds analysed for gene expression using Affymetrix Microarrays comparing the levels and timings of expression of genes involved in the inflammatory, granulation, remodelling, and maturation phases of healing and scarring (examples shown consist of comparison of ~300 genes for each phase).
