Efficacy and Tolerability of Fitostimoline in Two Different Forms (Soaked Gauzes and Cream) and Citrizan Gel in the Topical Treatment of Second-Degree Superficial Cutaneous Burns
Table 2
Lesion size and lesion disappearance (healing) at end of study in the efficacy population.
Fitostimoline soaked gauzes
Fitostimoline cream
Catalase gel
Fitostimoline pooled
Largest cross-diameter#
mean (95% CI)
0.1 (0.0–0.5)
0.4 (0.0–1.5)
2.3 (0.3–5.9)
0.2 (0.0–0.7)
Surface area#
mean (95% CI)
0.1 (0.0–0.3)
0.2 (0.0–0.7)
1.6 (0.1–4.5)
0.1 (0.1–0.3)
(%) of values = 0
71 (97.3)
65 (91.5)
60 (84.5)
136 (94.5)
(%) of values > 0
2 (2.7)
6 (8.5)
11 (15.5)
8 (5.5)
Overall comparison among groups
*
Fitostimoline gauzes/cream
RR (95% CI) 0.32 (0.066–1.51)
*
Fitostimoline pooled/Catalase gel
RR (95% CI) 0.35 (0.15–0.84)
*
#As percent ratio of baseline value. Back transformation of values calculated on angular-transformed data. Relative risk of not achieving lesion disappearance (size 0).
*Fisher’s exact test.
