Review Article

The Infant Skin Barrier: Can We Preserve, Protect, and Enhance the Barrier?

Table 3

Proinflammatory activity of commercially available cleansing products.

CleanserIL-1α (pg/mL)MTT cell proliferation assay

Mild baby cleanser100.5 ± 35.099.5%
Sensitive skin syndet bar1150.1 ± 0.16.5%

Mean (± standard deviation) IL-1α (pg/mL) released from in vitro skin tissue equivalents (EpiDerm, MatTek Corporation, Ashland, MA, USA) after exposure to various cleansing products. MTT cell proliferation (cell viability) assay data are also shown. The sensitive skin syndet bar had significantly more cell death than the mild baby cleanser, IL-1α: interleukin-1α.