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Dermatology Research and Practice
Volume 2012 (2012), Article ID 303275, 6 pages
http://dx.doi.org/10.1155/2012/303275
Clinical Study

Double-Blind, Placebo-Controlled, Randomized Study Comparing 0.0003% Calcitriol with 0.1% Tacrolimus Ointments for the Treatment of Endemic Pityriasis Alba

Dermatology Department, Hospital Central “Dr. Ignacio Morones Prieto”, Universidad Autónoma de San Luis Potosí, Avenida Carranza No. 2395, CP 78210, San Luis Potosi, Mexico

Received 1 December 2011; Revised 30 January 2012; Accepted 31 January 2012

Academic Editor: Iris Zalaudek

Copyright © 2012 Berenice Moreno-Cruz et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. Y. T. Jadotte and C. K. Janniger, “Pityriasis alba revisited: perspectives on an enigmatic disorder of childhood,” Cutis, vol. 87, no. 2, pp. 66–72, 2011.
  2. M. B. Weber, L. G. S. de Ávila, R. Albaneze, O. L. M. de Oliveira, B. D. Sudhaus, and T. F. Cestari, “Pityriasis alba: a study of pathogenic factors,” Journal of the European Academy of Dermatology and Venereology, vol. 16, no. 5, pp. 463–468, 2002. View at Publisher · View at Google Scholar
  3. F. Vargas-Ocampo, “Pityriasis alba: a histologic study,” International Journal of Dermatology, vol. 32, no. 12, pp. 870–873, 1993. View at Scopus
  4. R. F. Martín, A. Lugo-Somolinos, and J. L. Sánchez, “Clinicopathologic study on pityriasis alba,” Boletin de la Asociacion Medica de Puerto Rico, vol. 82, no. 10, pp. 463–465, 1990. View at Scopus
  5. V. di Lernia and C. Ricci, “Progressive and extensive hypomelanosis and extensive pityriasis alba: same disease, different names?” Journal of the European Academy of Dermatology and Venereology, vol. 19, no. 3, pp. 370–372, 2005. View at Publisher · View at Google Scholar
  6. R. Ruiz-Maldonado, “Hypomelanotic Conditions of the Newborn and Infant,” Dermatologic Clinics, vol. 25, no. 3, pp. 373–382, 2007. View at Publisher · View at Google Scholar · View at Scopus
  7. E. Galadari, M. Helmy, and M. Ahmed, “Trace elements in serum of pityriasis alba patients [3],” International Journal of Dermatology, vol. 31, no. 7, pp. 525–526, 1992. View at Scopus
  8. M. J. Du Toit and H. F. Jordaan, “Pigmenting pityriasis alba,” Pediatric Dermatology, vol. 10, no. 1, pp. 1–5, 1993. View at Scopus
  9. S. Urano-Suehisa and H. Tagami, “Functional and morphological analysis of the horny layer of pityriasis alba,” Acta Dermato-Venereologica, vol. 65, no. 2, pp. 164–167, 1985. View at Scopus
  10. A. G. Ochoa and F. Vargas Ocampo, “Treatment pityriasis alba with a combination of coal tar, diiodohydroxyquinoline and hydrocortisone,” Medicina Cutanea Ibero-Latino-Americana, vol. 8, no. 1–3, pp. 69–72, 1980. View at Scopus
  11. D. Rigopoulos, S. Gregoriou, C. Charissi, G. Kontochristopoulos, D. Kalogeromitros, and S. Georgala, “Tacrolimus ointment 0.1% in pityriasis alba: an open-label, randomized, placebo-controlled study,” British Journal of Dermatology, vol. 155, no. 1, pp. 152–155, 2006. View at Publisher · View at Google Scholar · View at Scopus
  12. W. H. Fujita, C. L. Mccormick, and A. Parneix-spake, “An exploratory study to evaluate the efficacy of pimecrolimus cream 1% for the treatment of pityriasis alba,” International Journal of Dermatology, vol. 46, no. 7, pp. 700–705, 2007. View at Publisher · View at Google Scholar · View at Scopus
  13. T. L. Clemens, J. S. Adams, and N. Horiuchi, “Interaction of 1,25-dihydroxyvitamin-D3 with keratinocytes and fibroblasts from skin of normal subjects and a subject with vitamin-D-dependent rickets, type II: a model for study of the mode of action of 1,25-dihydroxyvitamin D3,” Journal of Clinical Endocrinology and Metabolism, vol. 56, no. 4, pp. 824–830, 1983. View at Scopus
  14. E. L. Smith, N. C. Walworth, and M. F. Holick, “Effect of 1α,25-dihydroxyvitamin D3 on the morphologic and biochemical differentiation of cultured human epidermal keratinocytes grown in serum-free conditions,” Journal of Investigative Dermatology, vol. 86, no. 6, pp. 709–714, 1986.
  15. J. E. M. Körver, W. H. P. M. Vissers, D. W. A. Van Rens et al., “A double-blind, randomized quantitative comparison of calcitriol ointment and calcipotriol ointment on epidermal cell populations, proliferation and differentiation,” British Journal of Dermatology, vol. 156, no. 1, pp. 130–137, 2007. View at Publisher · View at Google Scholar · View at Scopus
  16. J. Reichrath, A. Perez, S. M. Müller et al., “Topical calcitriol (1,25-dihydroxyvitamin D3) treatment of psoriasis: an immunohistological evaluation,” Acta Dermato-Venereologica, vol. 77, no. 4, pp. 268–272, 1997. View at Scopus
  17. P. C. M. van de Kerkliof, “Reduction of epidermal abnormalities and inflammatory changes in psoriatic plaques during treatment with vitamin D3 analogs,” Journal of Investigative Dermatology Symposium Proceedings, vol. 1, no. 1, pp. 78–81, 1996. View at Scopus
  18. Z. A. Abdel-Malek, R. Ross, L. Trinkle, V. Swope, J. W. Pike, and J. J. Nordlund, “Hormonal effects of vitamin D3 on epidermal melanocytes,” Journal of Cellular Physiology, vol. 136, no. 2, pp. 273–280, 1988. View at Scopus
  19. E. Rizova and M. Corroller, “Topical calcitriol - Studies on local tolerance and systemic safety,” British Journal of Dermatology, vol. 144, no. 58, pp. 3–10, 2001. View at Scopus
  20. V. Lepe, B. Moncada, J. P. Castanedo-Cazares, M. B. Torres-Alvarez, C. A. Ortiz, and A. B. Torres-Rubalcava, “A double-blind randomized trial of 0.1% tacrolimus vs 0.05% clobetasol for the treatment of childhood vitiligo,” Archives of Dermatology, vol. 139, no. 5, pp. 581–585, 2003. View at Publisher · View at Google Scholar · View at Scopus
  21. H. Y. Kang and Y. M. Choi, “FK506 increases pigmentation and migration of human melanocytes,” British Journal of Dermatology, vol. 155, no. 5, pp. 1037–1040, 2006. View at Publisher · View at Google Scholar · View at Scopus
  22. H. Watabe, Y. Soma, Y. Kawa et al., “Differentiation of murine melanocyte precursors induced by 1,25-dihydroxyvitamin D3 is associated with the stimulation of endothelin B receptor expression,” Journal of Investigative Dermatology, vol. 119, no. 3, pp. 583–589, 2002. View at Publisher · View at Google Scholar · View at Scopus
  23. S. P. Hong, Y. Oh, M. Jung et al., “Topical calcitriol restores the impairment of epidermal permeability and antimicrobial barriers induced by corticosteroids,” British Journal of Dermatology, vol. 162, no. 6, pp. 1251–1260, 2010. View at Publisher · View at Google Scholar · View at Scopus
  24. N. Goksugur, B. Ozbostanci, and S. B. Goksugur, “Molluscum contagiosum infection associated with pimecrolimus use in pityriasis alba,” Pediatric Dermatology, vol. 24, no. 5, pp. E63–E65, 2007. View at Publisher · View at Google Scholar · View at Scopus
  25. M. Ambo, “Relapsing kaposi's varicelliform eruption and herpes simplex following facial tacrolimus treatment for atopic dermatitis,” Acta Dermato-Venereologica, vol. 82, no. 3, pp. 224–225, 2002. View at Publisher · View at Google Scholar · View at Scopus