Table 4: Local tolerability assessments.

Evaluator-assessed erythema, dryness, and peeling
GradeSeverityErythemaDrynessPeeling

0AbsentNo rednessNoneNo peeling
1SlightFaint red or pink coloration, barely perceptibleBarely perceptible dryness with no flakes or fissure formationMild localized peeling
2MildLight red or pink colorationEasily perceptible dryness with no flakes or fissure formationMild and diffuse peeling
3ModerateMedium red colorationEasily noted dryness and flakes but no fissure formationModerate and diffuse peeling
4SevereBeet red colorationEasily noted dryness with flakes and fissure formationModerate to prominent, dense peeling