Table 2: Drugs associated with melanocytic activation and subsequent longitudinal melanonychia. Table adapted from J. Andre, N. Lateur. Pigmented nail disorders [2].

Drug-induced melanonychia

ChemotherapeuticalsOthers

Bleomycin sulfateACTH
BusulfanAmodiaquine
CyclophosphamideAmorolfine
DacarbazineArsenic
Daunorubicin hydrochlorideChloroquine
DoxorubicinClofazimine
EtoposideClomipramine
5-fluorouracileCyclones
HydroxyureaFluconazole
ImatinibFluorides
Melphalan hydrochlorideGold salts
MethotrexateIbuprofen
Nitrogen mustardKetoconazole
NitrosoureaLamivudine
TegafurMepacrine
Mercury
MSH
Minocycline
PCB
Phenytoin
Phenothiazine
Psoralen
Roxithromycin
Steroids
Sulfonamide
Thallium
Timolol
Zidovudine