Serum Fatty Acids and Risk of Cutaneous Melanoma: A Population-Based Case-Control Study

Table 4

Odds ratio (OR) with 95% confidence intervals (CI) of melanoma by tertile of serum fatty acids percentage composition, adjusted for phototype, education and sun exposure.

	I^a	II		III		𝑃 trend
	OR	OR	(95% CI)	OR	(95% CI)
SFAs^b
Palmitic	1.00	0.79	(0.22–2.87)	0.71	(0.18–2.76)	0.440
Margaric (daturic)	1.00	0.49	(0.12–1.91)	1.66	(0.39–7.16)	0.646
Stearic	1.00	1.85	(0.46–7.43)	3.00	(0.56–16.07)	0.101
Arachidic	1.00	1.13	(0.20–6.54)	2.05	(0.45–9.40)	0.334
Lignoceric	1.00	0.24	(0.05–1.11)	0.38	(0.09–1.55)	0.552
MUFAs^b
Oleic	1.00	1.98	(0.51–7.60)	0.82	(0.22–3.08)	0.977
Nervonic	1.00	1.82	(0.31–10.78)	1.26	(0.15–10.48)	0.305
PUFAs^b
Linoleic	1.00	1.10	(0.34–3.58)	0.71	(0.20–2.45)	0.420
Arachidonic	1.00	0.50	(0.14–1.86)	1.10	(0.33–3.71)	0.459
EPA	1.00	1.65	(0.40–6.69)	0.64	(0.12–3.40)	0.785
DPA	1.00	0.49	(0.13–1.85)	0.73	(0.20–2.67)	0.697
DHA	1.00	0.42	(0.09–2.00)	0.44	(0.11–1.74)	0.581
Groupings
SFAs	1.00	0.28	(0.04–1.73)	1.56	(0.37–6.61)	0.848
MUFAs + PUFAs	1.00	0.62	(0.17–2.26)	0.52	(0.11–2.34)	0.686
MUFAs	1.00	1.33	(0.33–5.29)	0.71	(0.17–2.96)	0.876
PUFAs	1.00	0.95	(0.25–3.59)	0.98	(0.28–3.46)	0.850
SFAs/MUFAs + PUFAs	1.00	1.41	(0.33–6.05)	1.65	(0.43–6.33)	0.962
SFAs/PUFAs	1.00	0.88	(0.25–3.12)	1.31	(0.41–4.14)	0.692
n-3 PUFAs	1.00	0.70	(0.16–3.08)	0.95	(0.23–3.93)	0.531
n-6 PUFAs	1.00	0.64	(0.17–2.46)	0.97	(0.29–3.17)	0.775
n-3 PUFAs/n-6 PUFAs	1.00	1.55	(0.46–5.27)	1.04	(0.25–4.37)	0.504

^aReferent group.
^bSFAs: saturated fatty acids; MUFAs: monounsaturated fatty acids; PUFAs: polyunsaturated fatty acids.