The Effect of Weight Loss in Obese Patients with Chronic Stable Plaque-Type Psoriasis

Table 3

Clinical responses at weeks 4, 8, 12, and 24.

End point	Week 4	Week 8	Week 12	Week 24
End points reported by the physician
PASI 50 response
number of patients (%)	2 (20)	3 (30)	5 (50)	3 (30)
PASI 75 response
number of patients (%)	0 (0)	0 (0)	2 (20)	0 (0)
Mean PASI (SD)	5.2 (3.3)	3.2 (1.2)	3.2 (1.3)*	3.8 (1.6)*
“Most clear” or “mild” status
Number of patients (%)	5 (50)	7 (70)	8 (80)	7 (70)
End points reported by the patient
Percentage improvement in; Dermatology Life Quality index (SD)	34.1 (30.1)	46.9 (34.5)	62.5 (26.0)**	40.4 (33.5)*
Overall treatment satisfaction score (SD)	8.00 (2.4)**	9.2 (1.3)**	9.4 (1.1)**	8.6 (1.2)**
Rash satisfaction score (SD)	6.1 (3.1)*	8.6 (1.4)**	9.3 (0.8)**	8.8 (1.4)**
“Most clear” or “mild” status
Number of patients (%)	4 (40)	7 (70)	9 (90)	6 (60)

^∗𝑃<0.05 compared with baseline.
^∗∗𝑃<0.01 compared with baseline.