Table 3: Clinical responses at weeks 4, 8, 12, and 24.

End pointWeek 4Week 8Week 12Week 24

End points reported by the physician
PASI 50 response
 number of patients (%)2 (20)3 (30)5 (50)3 (30)
PASI 75 response
  number of patients (%)0 (0)0 (0)2 (20)0 (0)
Mean PASI (SD)5.2 (3.3)3.2 (1.2)3.2 (1.3)*3.8 (1.6)*
“Most clear” or “mild” status
 Number of patients (%)5 (50)7 (70)8 (80)7 (70)

End points reported by the patient
Percentage improvement in
Dermatology Life Quality index (SD)
34.1 (30.1)46.9 (34.5)62.5 (26.0)**40.4 (33.5)*
Overall treatment satisfaction score (SD)8.00 (2.4)**9.2 (1.3)**9.4 (1.1)**8.6 (1.2)**
Rash satisfaction score (SD)6.1 (3.1)*8.6 (1.4)**9.3 (0.8)**8.8 (1.4)**
“Most clear” or “mild” status
 Number of patients (%)4 (40)7 (70)9 (90)6 (60)

compared with baseline.
compared with baseline.