Clinical Study

Five-Year Retrospective Review of Acute Generalized Exanthematous Pustulosis

Table 1

Acute generalized exanthematous pustulosis validation score of the EuroSCAR study group [1].

MorphologyScore

Pustules
 Typical2
 Compatible1
 Insufficient0
Erythema
 Typical2
 Compatible1
 Insufficient0
Distribution/pattern
 Typical2
 Compatible1
 Insufficient0
Pustular desquamation
 Yes1
 No/insufficient0
Course
 Mucosal involvement
 Yes−2
 No0
Acute onset (<10 d)
 Yes0
 No−2
Resolution (<15 d)
 Yes0
 No−4
Fever > 38°C
 Yes1
 No0
Neutrophils > 7,000/mm
 Yes1
 No0
Histology
 Other diseases−10
 Not representative/no histopathology0
 Exocytosis of neutrophils1
Subcorneal and/or intraepidermal nonspongiform or unspecified pustule(s) with papillary edema or subcorneal and/or intraepidermal spongiform or unspecified pustules(s) without papillary edema2
Spongiform subcorneal and/or intraepidermal pustule(s) with papillary edema3

Interpretation: <0: no AGEP, 1–4: possible, 5–7: probable, and 8–12: definite.