Efficacy and Safety of the Traditional Japanese Medicine Keigairengyoto in the Treatment of Acne Vulgaris

Figure 1

Effect of Keigairengyoto on the number of acne rashes. Patients were randomized into a conventional treatment group (control group, white circles) and a group with conventional treatment and Keigairengyoto (KRT group, filled circles), and they were treated for 12 weeks. The amount of inflammatory and noninflammatory acne on the face was counted at baseline (study entry) and at weeks 2, 4, 8, and 12. Time-dependent changes of inflammatory (a), noninflammatory (b), and total (c) acne are shown as a reduction in the number of the respective rashes. Data are presented as the mean ± standard error. The number of patients at the time of each control and KRT group evaluation is as follows: pretreatment: control 28 and KRT 24; week 2: 24 and 23; week 4: 20 and 22; week 8: 21 and 19; and week 12: 16 and 14. P<0.05, Wilcoxon rank-sum test.

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