Efficacy of Chronic Antidepressant Treatments in a New Model of Extreme Anxiety in Rats

Table 4

Effects of acute diazepam (DZP) treatment (3 mg/kg, IP, 𝑛=9, median with limits of interquartile range values). Mann-Whitney U test: *𝑃<0.05 (DZP versus vehicle). Wilcoxon-test: ^##𝑃<0.01 (test versus baseline). Data were expressed as median with limits of interquartile range values.

Measures	Baseline (before treatment)		Test (after treatment)
	Vehicle (𝑛=9)	DZP (𝑛=9)	Vehicle (𝑛=9)	DZP (𝑛=9)
Number of jumps	13.5 (12–17)	15.5 (8–28)	15 (10–19)	6^*## (4–14)
Latency before the first jump (s)	15.5 (12–25)	23.5 (6–34)	11 (6–20)	28* (12–78)
Immobility (s)	84 (44–129)	85.5 (52–120)	129.5^## (90–176)	130^## (83–171)