Neuromagnetic Indication of Dysfunctional Emotion Regulation in Affective Disorders
Figure 1
(a) Time course of field strength around picture onset at 0 ms for watch-neutral (solid black lines), watch-unpleasant (solid blue lines), and down-regulate-unpleasant conditions (dotted blue lines) for healthy control participants (HC). The left panel illustrates left-hemisphere sensors, the right panel right-hemisphere sensors. In- and outgoing magnetic fields explain the opposite direction of the effect. Periods during which conditions differ significantly are marked in yellow for watch-unpleasant versus watch-neutral (Emotion effect) and in brown for watch-unpleasant versus down-regulate-unpleasant (Instruction effect). The center panel presents t-maps projected onto a schematic top view (left = left) testing watch-unpleasant versus watch-neutral (Emotion effect) 300–600 ms after picture onset (top) and comparing watch-unpleasant versus down-regulate-unpleasant (Instruction effect) 600–1000 ms after picture onset (bottom). Sensors defining the significant cluster are marked by open circles). (b) Time course of field strength preceding cross cue onset (−2000 ms) to picture onset (0) ms for watch-neutral (solid black line), watch-unpleasant (solid blue line), and down-regulate-unpleasant (dotted blue line) conditions for HC group. The gray bar marks the epoch of significant differences between conditions. t-maps projected onto a schematic top view are plotted below, testing down-regulate-unpleasant versus watch-unpleasant conditions and testing down-regulate-unpleasant versus watch-neutral. Red and blue colors represent sensor clusters that show significant () differences in field strength between conditions. Sensors defining the significant clusters are marked by open circles. The different direction of effects explains positive and negative t-values referring to the left (positive t-values, red) and right (negative t-values, blue) hemisphere ERF.
