Quality of Life in Bipolar Type I Disorder in a One-Year Followup
Table 3
Correlation coefficients of the physical domain scores of WHOQOL-BREF with the severity of clinical symptoms and level of functioning in bipolar disorder group at baseline, 4-, 8-, 12-month assessments.
Assessment
Model
Unstandardized coefficients
Standardized coefficients
value
R square
Adjusted R square
Collinearity statistics (VIF)
St. Er
Beta
Baseline ()
1
HDRS
−1.87
0.35
−0.59
−5.42
<0.001
0.59
0.35
0.34
1.00
2
HDRS
−2.11
0.33
−0.67
−6.41
<0.001
0.67
0.45
0.43
1.06
CGI
5.30
1.70
0.33
3.12
<0.01
1.06
4-month ()
1
HDRS
−0.16
0.07
−0.33
−2.36
<0.05
0.33
0.11
0.09
1.00
8-month ()
1
HDRS
−1.72
0.35
−0.61
−4.97
<0.001
0.61
0.37
0.36
1.00
2
HDRS
−2.19
0.33
−0.77
−6.61
<0.001
0.72
0.52
0.50
1.18
YMRS
0.99
0.27
0.43
3.63
<0.001
1.18
12-month ()
1
HDRS
−0.97
0.27
−0.48
−3.60
<0.001
0.48
0.23
0.21
1.00
2
HDRS
−1.17
0.25
−0.58
−4.67
<0.001
0.62
0.39
0.37
1.07
Sex
−13.93
4.29
−0.41
−3.25
<0.01
1.07
HDRS: Hamilton-Depression Rating Scale. CGI: Clinical Global Impression. YMRS: Young Mania Rating Scale.