Table 4: Correlation coefficients of the psychological domain scores of WHOQOL-BREF with the severity of clinical symptoms and level of functioning in bipolar disorder group at baseline, 4-, 8-, 12-month assessments.

AssessmentModelUnstandardized coefficientsStandardized coefficients value squareAdjusted squareCollinearity statistics (VIF)
St. ErBeta

Baseline ( )1HDRS−1.620.49−0.41−3.30<0.010.410.170.151.00
2HDRS−1.800.45−0.45−3.98<0.0010.56
0.31
0.29
1.01
YMRS0.880.260.383.38<0.0011.01

4-month ( )1HDRS−1.380.39−0.47−3.58<0.0010.470.220.201.00

8-month ( )1HDRS−1.650.39−0.55−4.28<0.0010.550.300.291.00
2HDRS−2.160.37−0.72−5.84<0.0010.68
0.47
0.44
1.18
YMRS1.090.310.443.56<0.0011.18

12-month ( )1HDRS−1.010.24−0.54−4.24<0.0010.540.290.281.00

HDRS: Hamilton-Depression Rating Scale.
YMRS: Young Mania Rating Scale.