Table 2: Commonly adopted strategies for managing sexual dysfunction associated with antidepressant drugs. Questionnaire survey, US psychiatrists, expertise in managing sexual dysfunction [41]. Percentages indicate the proportion of physicians using that strategy as their preferred intervention.

Dysfunction Most frequently used treatment strategies first-, second-, and third-line interventions Impaired libido—men and women First. Adding a dopaminergic agent (37.9%) Second. Switching to another antidepressant (mostly bupropion) (44.8%) Third. Switching to another antidepressant (mostly bupropion) (31%) Impaired arousal—women First. Adding a dopaminergic agent (amantadine, bupropion, stimulants) (37.9%) Second. Adding a dopaminergic agent (amantadine, bupropion, stimulants) (20.4%) Third. Switching to another antidepressant (mostly bupropion) (34.5%) Impaired arousal—men First. Adding a dopaminergic agent (mostly stimulants) (31%) Second. Switching to another antidepressant (mostly bupropion) (31%) Third (a). Switching to another antidepressant (mostly bupropion) (37.9%) Third (b). Adding sildenafil, tadalafil, or vardenafil (mostly sildenafil or all three) (37.9%) (a and b used by equal number of experts as a third choice) Impaired orgasm—women First. Adding a dopaminergic agent (amantadine, stimulants) (34.5%) Second. Switching to another antidepressant (mostly bupropion) (31%) Third. Switching to another antidepressant (mostly bupropion) (27.5%) Impaired orgasm —men First (a). Adding a dopaminergic agent (stimulants) (31%) First (b). Decreasing the dose of antidepressant (31%) Second. Switching to another antidepressant (mostly bupropion) (34.5%) Third. Switching to another antidepressant (mostly bupropion) (31%) (a and b used by equal number of experts as a first choice)