Carbon Dioxide Insufflation in Routine Colonoscopy Is Safe and More Comfortable: Results of a Randomized Controlled Double-Blinded Trial
Table 2
Parameters of colonoscopy in CO2 and room air group.
CO2 group
Room air group
value
Propofol
134 mg ± 56
120 mg ± 120
.9
Nasal oxygen substitution if O2 saturation <90%
10%
20.2%
.02
Ileum intubation rate
95.5%1
97.2% 1
.22
Time to ileum
min
min
.18
Withdrawal time
min
min
.99
Intervention time
min
min
.99
Polyps
68.2%
68.8%
.11
>1 cm
8.2%
7.3%
0.5–1 cm
17.3%
16.6%
<0.5 cm
63.6%
66.1%
Findings
.77
Carcinoma
0.9%
1.8%
Relevant polyp2
10.9%
7.3%
Small adenoma3
34.5%
33.9%
Hyperplastic
13.6%
14.7%
CO2 (mmHg)
at start
.59
at ileum
.62
end of examination
.01
Maximal CO2 rise
.77
10.9% stenosis (e.g., tumor, or sigmoid stenosis due to diverticulosis) in both groups, reaching coecum in 99% in both groups. 2Relevant polyps defined as polyp >1 cm, serrated, and villous ± high-grade dysplasia. 3Polyps size <1 cm.