The Learning Curve of Gastric Intestinal Metaplasia Interpretation on the Images Obtained by Probe-Based Confocal Laser Endomicroscopy

Table 3

Comparing the learning curve of different studies of CLE in the GI tract.

	Present study	Kuiper et al.; Gastrointest Endosc 2012 [5]	Buchner et al.; Gastrointest Endosc 2011 [6]	Neumann et al. Histol Histopathol 2011 [7]	Gaddam et al. Am J Gastroenterol 2011 [8]
Type of confocal laser	pCLE	iCLE	pCLE	pCLE	pCLE
Tissue	Stomach (GIM)	Colonic polyp	Colonic polyp	Colon (IBD)	Esophagus (Barrett)
Number of reader	5	3	11	2	3
Number of center	1	1	3	1	1
Type of study	Offline study	Offline study	Offline study	Offline study	Offline study
Training duration	1 hr	N/A	2 hr	N/A	1 hr
Intraobserver agreement (κ)	N/A	Yes (0.68–0.84)	N/A	N/A	N/A
Interobserver agreement (κ)	Yes (0.52–0.86)	Yes (0.67–0.73)	N/A	N/A	Yes (0.48–0.68)
Conclusion	Easy to learn	Easy to learn	Easy to learn	Easy to learn	Short learning curve

pCLE: probe-based confocal laser endomicroscope, iCLE: integrated confocal laser endomicroscope, GIM: gastric intestinal metaplasia, IBD: inflammatory bowel disease, and N/A: no data.