Table 3: Comparing the learning curve of different studies of CLE in the GI tract.

Present study Kuiper et al. Gastrointest Endosc 2012 [5] Buchner et al. Gastrointest Endosc 2011 [6] Neumann et al. Histol Histopathol 2011 [7] Gaddam et al. Am J Gastroenterol 2011 [8] Type of confocal laser pCLE iCLE pCLE pCLE pCLE Tissue Stomach (GIM) Colonic polyp Colonic polyp Colon (IBD) Esophagus (Barrett) Number of reader 5 3 11 2 3 Number of center 1 1 3 1 1 Type of study Offline study Offline study Offline study Offline study Offline study Training duration 1 hr N/A 2 hr N/A 1 hr Intraobserver agreement (κ) N/A Yes (0.68–0.84) N/A N/A N/A Interobserver agreement (κ) Yes (0.52–0.86) Yes (0.67–0.73) N/A N/A Yes (0.48–0.68) Conclusion Easy to learn Easy to learn Easy to learn Easy to learn Short learning curve

pCLE: probe-based confocal laser endomicroscope, iCLE: integrated confocal laser endomicroscope, GIM: gastric intestinal metaplasia, IBD: inflammatory bowel disease, and N/A: no data.