Table 3: Comparison between digital chromoendoscopy (FICE) and real-time chromoendoscopy (indigo carmine) in differentiating neoplastic from non-neoplastic lesions.

FICE (DCE)Indigo carmine (CE)

Accuracy % (95% CI)92.6 (87.3–98.0)94.2 (90.0–98.4)
Sensitivity % (95% CI)91.7 (82.7–96.9)96.5 (90.1–99.3)
Specificity % (95% CI)95.7 (78.1–99.9)88.2 (72.5–96.7)
PPV % (95% CI)98.5 (92–100)95.4 (88.6–98.7)
NPV % (95% CI)78.6 (59–91.7)90.9 (75.7–98.1)
Kappa (95% CI)0.81 (0.68–0.95)0.86 (0.75–0.96)

95% CI: 95% confidence interval; FICE: Fujinon intelligent color enhancement; DCE: digital chromoendoscopy; CE: real-time chromoendoscopy; PPV: positive predictive value; NPV: negative predictive value.