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Figure 2: Confocal imaging of COX-2 expression. Confocal microscopy of COX-2 expression in unprocessed tissue specimens including healthy control tissue, inflamed colon tissue from AOM + DSS-treated animals and tumor tissue from AOM + DSS-treated animals and APCmin mice. The white bar represents 50 μm. The white arrows indicate individual cells in the stroma of inflamed colon or tumor tissue with high COX-2 expression. TC: tumor cells.