Review Article

Endoscopic Papillary Large Balloon Dilation Reduces the Need for Mechanical Lithotripsy in Patients with Large Bile Duct Stones: A Systematic Review and Meta-Analysis

Table 4

Sensitivity analysis of the primary and secondary outcomes stratified by the type of the studies.

Relative risk (EPLBD + ES versus ES), (95% CI)
Retrospective studiesRandomized clinical trialsCombined

Overall clearance of bile duct stone1.06 (0.95, 1.01)0.98 (0.97, 1.01)1.01 (0.97, 1.05)
Clearance of the stones at 1st session1.29 (1.01, 1.46)0.99 (0.91, 1.07)1.11 (0.98, 1.25)
Need for ML0.31 (0.22, 0.44)0.73 (0.52, 1.03)0.49 (0.32, 0.74)
Overall complication rate0.57 (0.36, 0.91)0.59 (0.36, 0.95)0.58 (0.41, 0.81)