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Evidence-Based Complementary and Alternative Medicine
Volume 5 (2008), Issue 1, Pages 91-94
http://dx.doi.org/10.1093/ecam/nem003
Original Article

Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. Roots

Pharmacognosy and Phytochemistry Division, Faculty of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar 125001, India

Received 29 April 2006; Accepted 11 January 2007

Copyright © 2008 Neeru Vasudeva and S. K. Sharma. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Ancient literature mentions the use of a number of plants/preparations for fertility regulation. Some local contraceptive agents have also been described in Ayurvedic and Unani texts. Documented experiments or clinical data are, however, lacking. Therefore, the present study was undertaken to explore the antifertility and estrogenic activity of ethanolic extract of the roots of Hibiscus rosa-sinensis Linn. A strong anti-implantation (inhibition 100%) and uterotropic activity was observed at the dose level of 400 mg/kg body weight. Histological studies were carried out to confirm this effect.