Ethanol Extract of the Flower Chrysanthemum morifolium Augments Pentobarbital-Induced Sleep Behaviors: Involvement of Cl⁻ Channel Activation

Table 1

Effects of EFC on sleep onset of mice treated by subhypnotic doses of pentobarbital (28 mg/kg, i.p.).

Group	Dose (mg/kg)	No. falling asleep/total	Sleep time (min)
Control	0	6/15	23.3±1.8
Muscimol	0.2	13/14**	41.2±4.2 ***
EFC	20	7/14	28.0±4.0
	50	7/14	29.6±3.2
	100	11/13*	35.9±3.6 *

Each value represents the mean (±S.E.M.) of 13–15 observations. *𝑃<.05, **𝑃<.01, ***𝑃<.005 versus control.