Dieckol from Ecklonia cava Regulates Invasion of Human Fibrosarcoma Cells and Modulates MMP-2 and MMP-9 Expression via NF-κB Pathway
Figure 5
Effect of dieckol on the NF-κB and AP-1 cell signaling pathway and TIMP-1, -2 expressions in HT1080 cells. (a) Nucleus NF-κB (p65 and p50) and IκB (p-IκB-α) protein expressions in the dieckol treated HT1080 cells. (b) (c-jun), MAPK pathway (ERK, JNK, p38). (c) Western blot analysis of TIMP-1 and TIMP-2.