Original Article

Endogenous Opiates in the Nucleus Tractus Solitarius Mediate Electroacupuncture-Induced Sleep Activities in Rats

Figure 1

The effects of low-frequency (10 Hz) stimulation by EA at Anmian (EX17) acupoints on vigilance states. The 10 Hz EA enhanced NREM sleep during post-manipulation 5–8 h during the subsequent dark period. *Represents a statistically significant difference between the values obtained from ipketamine PFS and ipPFS PFS. The shaded area represents the values of mean     SEM. #Depicts a statistically significant difference between the values obtained from ipketamine PFS EA and ipketamine PFS. The black horizontal bar on the x-axis represents the dark period of the 12 : 12 h light : dark cycle. WAKE, wakefulness.
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