Evidence-Based Complementary and Alternative Medicine

Original Article

Assessment of the Antioxidant and Reactive Oxygen Species Scavenging Activity of Methanolic Extract of Caesalpinia crista Leaf

Table 1

Reactive oxygen species scavenging and iron chelating activity (IC₅₀ values) of C. crista and reference compounds.


Activity	Extract/reference

Hydroxyl radical (OH^•) scavenging	Caesalpinia crista	0.44 ± 0.1 (6)
Hydroxyl radical (OH^•) scavenging	Mannitol	0.85 ± 0.02 (6)***
Superoxide anion () scavenging	Caesalpinia crista	24.9 ± 0.98 (6)
Superoxide anion () scavenging	Quercetin	47.38 ± 0.68 (6)***
Nitric oxide radical (NO) scavenging	Caesalpinia crista	33.72 ± 0.85 (6)
Nitric oxide radical (NO) scavenging	Curcumin	97.12 ± 3.09 (6)***
Singlet oxygen (¹O₂) scavenging	Caesalpinia crista	61.13 ± 3.24 (6)
Singlet oxygen (¹O₂) scavenging	Lipoic acid	49.48 ± 8.56 (6)**
Hypochlorous acid (HOCl) scavenging	Caesalpinia crista	170.51 ± 4.68 (6)
Hypochlorous acid (HOCl) scavenging	Ascorbic acid	198.42 ± 10.71 (6)**
Iron chelating activity	Caesalpinia crista	279.85 ± 4.72 (6)
Iron chelating activity	EDTA	1.27 ± 0.05 (6)***

of IC₅₀ values of all activities is g/mL, except OH^• scavenging where unit is mg/mL. Data are expressed as mean ± SD. Data in parentheses indicate number of independent assays. EDTA represents ethylenediamine tetraacetic acid.
** P .01; *** versus C. crista.