Assessment of the Antioxidant and Reactive Oxygen Species Scavenging Activity of Methanolic Extract of Caesalpinia crista Leaf

Table 2

Effect of the methanolic extract of C. crista leaves on the activities of antioxidant enzymes and reduced glutathione content in liver of normal mice.

Tested parameter	Group I	Group II	Group III	Group IV
SOD (U/mg protein)	1.22 ± 0.54	2.61 ± 0.2**	2.96 ± 0.19***	3.37 ± 0.2***
CAT (U/mg protein)	0.9 ± 0.72	1.19 ± 0.09	1.5 ± 0.37*	1.66 ± 0.43*
GST (U/mg protein)	0.22 ± 0.05	0.31 ± 0.1	0.31 ± 0.08*	0.42 ± 0.08***
GSH (μg/mg protein)	1.16 ± 0.04	1.43 ± 0.12*	1.78 ± 0.08***	2.1 ± 0.09***

Group I: control group; Group II: mice treated orally with the extract in a dose of 10 mg/kg body weight; Group III: mice treated orally with the extract in a dose of 50 mg/kg body weight; Group IV: mice treated orally with the extract in a dose of 100 mg/kg body weight. Results are expressed as mean ± SD for six mice in each group.
* P < .05, **𝑃<.01, ^∗∗∗𝑃<.001 compared with control.