Preventive Effect of Pine Bark Extract (Flavangenol) on Metabolic Disease in Western Diet-Loaded Tsumura Suzuki Obese Diabetes Mice

Figure 2

The effect of Flavangenol on the accumulation of adipose tissue in mice. (A) X-ray CT images of subcutaneous and visceral fat at 12 weeks. The yellow color shows the subcutaneous fat and the deep pink color shows the visceral fat. (a)TSNO-MF; (b)TSOD-MF; (c) TSOD-WTD; (d) TSOD-WTD-Flavangenol 3%; (e): TSOD-WTD-Flavangenol 5%. (B) Time-course of subcutaneous and visceral fat accumulation. closed diamond: TSNO-MF; closed square: TSOD-MF; closed triangle: TSOD-WTD; open square: TSOD-WTD-Flavangenol 3%; open triangle: TSOD-WTD-Flavangenol 5%. Data represent the mean ± SD of 8-9 animals. **P < .01, significant differences from the TSOD-MF group; ^##P < .01, significant differences from the TSOD-WTD group.