Research Article

Increased Survivorship and Altered Cytokine Profile from Treatment of Influenza A H1N1-Infected Mice with Ekybion: A Drug Complex of Natural Extracts and Inorganic Compounds

Figure 4

Immunomodulatory effects of Ekybion. Lung tissue previously harvested at day 2 postinfection was homoginized and tested for expression levels of 22 cytokines. Only those cytokines with significant changes are shown. (a) Expression levels were determined initially by membrane-based antibody array (RayBio) and normalized to uninfected untreated control animals. (b) Subsequent analysis was performed by multiplex bead-based cytokine detection (Millipore), and expression levels are displayed as pg/g lung tissue. 2 min = 1X treatment for 2 min, 4 min = 1X treatment for 4 min, and 10X = 10X treatment for 2 min ( by Student’s -test, = 2-3 per group).
192079.fig.004a
(a)
192079.fig.004b
(b)