The Traditional Japanese Medicine Rikkunshito Promotes Gastric Emptying via the Antagonistic Action of the 5-HT3 Receptor Pathway in Rats
Figure 1
Amelioration of the 5-HT- (a) and dopamine-induced (b) delay in gastric emptying by rikkunshito in rats: (a) rikkunshito administration at a high dose of 500 mg kg−1 ameliorated the 5-HT (0.02 mg kg−1)-induced delay in gastric emptying, but rikkunshito at a lower dose (125 or 250 mg kg−1) did not; (b) rikkunshito at any of the doses used in this study did not reverse the delay caused by dopamine (0.4 mg kg−1); each column represents the mean ± SEM. of eight rats. *P < .01: significantly different from the control group.
