Original Article

The Traditional Japanese Medicine Rikkunshito Promotes Gastric Emptying via the Antagonistic Action of the 5-HT3 Receptor Pathway in Rats

Figure 3

Amelioration of the 5-HT- (a) and dopamine-induced (b) delay in gastric emptying by ondansetron in rats: (A) administration of ondansetron (0.4 or 4.0 mg kg−1) ameliorated the 5-HT (0.02 mg kg−1)-induced delay in gastric emptying; (B) ondansetron at any of the doses used in this study did not reverse the delay caused by dopamine (0.4 mg kg−1). Each column represents the mean ± SEM of eight rats. **P < .01, *P < .05: significantly different from the control group.
248481.fig.003a
(a)
248481.fig.003b
(b)