Traditional Medicine to Modern Pharmacogenomics: Ayurveda Prakriti Type and CYP2C19 Gene Polymorphism Associated with the Metabolic Variability

Table 1

Genotype frequencies of CYP2C19 gene polymorphism in V, P and K Prakriti.

CYP2C19 Genotype	Phenotype frequency		P	Phenotype frequency		P	Phenotype frequency		P
	Vata n = 26 (%)	Kapha + Pitta n = 106 (%)		Pitta n = 43 (%)	Kapha + Vata n = 89 (%)		Kapha n = 63 (%)	Pitta + Vata n = 69 (%)
1/1	11 (42.31)	34 (32.08)	.360	15 (34.88)	30 (33.70)	1.000	19 (30.16)	26 (37.68)	.462
1/2	12 (46.15)	47 (44.34)	1.000	22 (51.16)	37 (41.57)	.351	25 (39.68)	34 (49.27)	.296
1/3	—	2 (1.89)	1.000	2 (4.65)	—	.104	—	2 (2.89)	.497
2/2	3 (11.54)	22 (20.75)	.404	4 (9.32)	21 (23.59)	.059	18 (28.57)	7 (10.14)	.008
2/3	—	1 (0.94)	1.000	—	1 (1.12)	1.000	1 (1.59)	—	.477
3/3	—	—	—	—	—	—	—	—	—