Original Article
Screening for Antiviral Activities of Isolated Compounds from Essential Oils
Table 1
Selectivity indices of anise oil and selected phenylpropanoids and sesquiterpenes against HSV-1
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| | Essential oil/compound | Max. non-cytotoxic conc. (g mL−1) ± SD | TC50 (g mL−1) ± SD | IC50 (g mL−1) ± SD | SI |
| | Star anise oil | 100 ± 8.0 | 160 ± 30.7 | 1 ± 0.1 | 160 | | Trans-anethole | 70 ± 3.0 | 100 ± 6.4 | 20 ± 1.1 | 5 | | Eugenol | 60 ± 11.1 | 85 ± 8.1 | 35 ± 6.2 | 2.4 | | β-Eudesmol | 9 ± 1.3 | 35 ± 5.4 | 6 ± 0.3 | 5.8 | | Farnesol | 10 ± 0.4 | 40 ± 3.7 | 3.5 ± 0.1 | 11.4 | | β-Caryophyllene | 10 ± 0.1 | 35 ± 2.3 | 0.25 ± 0.0 | 140 | | β-Caryophyllene oxide | 9 ± 1.1 | 18 ± 1.2 | 0.7 ± 0.1 | 25.7 |
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Experiments were repeated independently and data presented are the mean of three experiments.
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