Toxicity Profile of the Aqueous Ethanol Root Extract of Corrigiola telephiifolia Pourr. (Caryophyllaceae) in Rodents
Table 3
Changes in the mean bodyweight of rats after daily oral treatment (40 days) with Corrigiola telephiifolia extract.
Corrigiola telephiifolia (mg/kg bodyweight)
Control
5
70
2000
Females
Days
D1
199.4 ± 4.8
200.3 ± 3.8
216.0 ± 3.5
187.1 ± 3.6
D5
205.4 ± 4.9
206.4 ± 4.7
214.0 ± 4.2
175.0 ± 3.
D10
210.0 ± 4.6
210.9 ± 4.5
218.0 ± 5.2
175.1 ± 3.
D15
210.0 ± 5.9
210.2 ± 5.3
220.0 ± 5.2
176.7 ± 3.
D20
216.8 ± 6.
217.1 ± 6.
227.0 ± 5.6
182.1 ± 3.
D25
220.1 ± 6.
221.0 ± 6.
228.0 ± 4.
185.5 ± 4.
D30
220.3 ± 6.
221.5 ± 6.
230.5 ± 5.
187.7 ± 5.
D35
222.9 ± 4.
224.1 ± 4.
231.0 ± 4.
189.3 ± 4.
D40
221.5 ± 4.
223.8 ± 5.
229.0 ± 4.
190.9 ± 3.
Males
Days
D1
242.8 ± 2.9
245.1 ± 2.6
247.4 ± 3.5
250.5 ± 2.4
D5
251.7 ± 3.2
253.6 ± 3.1
246.7 ± 2.8
242.0 ± 2.
D10
253.2 ± 3.
256.5 ± 3.
253.7 ± 3.
245.6 ± 2.4
D15
255.5 ± 3.
259.4 ± 4.
264.6 ± 4.
249.1 ± 4.1
D20
261.2 ± 4.
264.3 ± 5.
267.9 ± 5.
251.6 ± 6.3
D25
270.7 ± 5.
274.6 ± 5.
269.3 ± 5.
254.3 ± 4.
D30
273.6 ± 6.
277.1 ± 5.
274.4 ± 5.
259.1 ± 3.
D35
276.6 ± 7.
280.3 ± 6.
277.0 ± 6.
264.1 ± 3.
D40
277.5 ± 6.
281.2 ± 6.
277.8 ± 6.
266.9 ± 3.
Values are expressed as mean ± SEM. The different superscript letters indicate statistically significant differences in the Student’s -test. s compared with the control group; s compared with the initial weight of rats on the first day (D1) of the treatment for each group.
