Toxicity Profile of the Aqueous Ethanol Root Extract of Corrigiola telephiifolia Pourr. (Caryophyllaceae) in Rodents
Table 6
Effect of a forty-day oral administration of Corrigiola telephiifolia extract on biochemical parameters of male Wistar rats
Corrigiola telephiifolia (mg/kg/day)
Control
5
70
2000
Parameter
Na mmol/L
140.9 ± 0.6
139.5 ± 0.3
138.3 ± 0.
135.1 ± 1.
Cl mmol/L
111.3 ± 0.6
110.7 ± 0.2
105.0 ± 0.
103.4 ± 0.
K mmol/L
8.0 ± 0.3
8.0 ± 0.4
8.0 ± 0.5
7.7 ± 0.4
Mg mmol/L
1.5 ± 0.1
1.6 ± 0.1
1.9 ± 0.1
1.4 ± 0.1
Ca mmol/L
1.7 ± 0.1
1.7 ± 0.1
1.9 ± 0.1
1.8 ± 0.1
Iron mol/L
28.9 ± 1.6
28.7 ± 1.5
28.6 ± 2.2
32.7 ± 2.3
Ph.org mmol/L
4.4 ± 0.4
4.3 ± 0.4
4.1 ± 0.4
4.5 ± 0.5
Total protein g/L
66.4 ± 1.2
66.5 ± 1.0
67.9 ± 1.1
66.6 ± 1.7
Glucose mmol/L
6.6 ± 0.2
6.5 ± 0.3
6.4 ± 0.4
6.9 ± 0.5
Urea mmol/L
5.0 ± 0.3
5.1 ± 0.2
5.1 ± 0.2
4.7 ± 0.3
Creatinine mol/L
23.2 ± 1.7
23.1 ± 0.9
23.0 ± 0.7
26.8 ± 2.0
Bicarbonates mm Hg
21.3 ± 0.8
21.5 ± 0.7
22.1 ± 1.0
20.6 ± 1.3
Uric acid mol/L
271.1 ± 29.2
264.8 ± 24.5
251.4 ± 21.4
200.9 ± 35.8
Total cholesterol mmol/L
1.5 ± 0.1
1.5 ± 0.1
1.4 ± 0.1
1.7 ± 0.1
Triglycerides mmol/L
1.2 ± 0.1
1.2 ± 0.1
1.1 ± 0.1
1.2 ± 0.2
Bilirubin mol/L
27.5 ± 1.3
27.8 ± 1.4
28.1 ± 1.5
31.9 ± 2.0
AST UI/L
77.9 ± 6.9
79.5 ± 7.3
81.9 ± 7.1
114.5 ± 23.5
ALT UI/L
25.0 ± 1.4
24.7 ± 1.5
22.2 ± 1.3
41.3 ± 9.6
ALP UI/L
146.3 ± 23.6
153.6 ± 21.3
164.1 ± 15.8
173.4 ± 28.3
GGT UI/L
1.5 ± 0.2
1.5 ± 0.1
1.4 ± 0.1
2.2 ± 0.4
C. telephiifolia extract was administered daily for 40 consecutive days to rats . Data are expressed as mean ± S.E.M. ignificantly different from the control
