Protective Effects of Emodin and Chrysophanol Isolated from Marine Fungus Aspergillus sp. on Ethanol-Induced Toxicity in HepG2/CYP2E1 Cells

Figure 5

Effects of emodin and chrysophanol on the intracellular glutathione contents in the absence and presence of ethanol treatments. The HepG2/CYP2E1 cells pretreated with emodin and chrysophanol at various concentrations for 1 h prior to the treatment with 1.0 M ethanol for 48 h. The cell lysates in 5% metaphosphoric acid were used for the determination of intracellular GSH content for 48 h. Results are means ± standard error of three independent experiments.